Module #1 Introduction to Advanced Clinical Trial Design Overview of advanced clinical trial design concepts and importance in modern clinical research
Module #2 Review of Basic Clinical Trial Design Refresher on fundamental concepts of clinical trial design, including parallel group, crossover, and longitudinal designs
Module #3 Advanced Randomization Techniques Discussion of blocked randomization, stratified randomization, and adaptive randomization methods
Module #4 Covariate-Adaptive Randomization In-depth exploration of covariate-adaptive randomization methods, including minimization and response-adaptive randomization
Module #5 Factorial Designs Introduction to factorial designs, including 2x2 and 2k factorial designs, and their applications in clinical trials
Module #6 Fractional Factorial Designs Analysis of fractional factorial designs, including resolution III and IV designs, and their use in clinical trials
Module #7 Response-Adaptive Designs Discussion of response-adaptive designs, including Bayesian and frequentist approaches, and their applications in clinical trials
Module #8 Platform Trials Introduction to platform trials, including their design, conduct, and analysis, and their applications in precision medicine
Module #9 Master Protocols In-depth exploration of master protocols, including their design, conduct, and analysis, and their applications in oncology and other fields
Module #10 Umbrella Trials Overview of umbrella trials, including their design, conduct, and analysis, and their applications in precision medicine
Module #11 Basket Trials Discussion of basket trials, including their design, conduct, and analysis, and their applications in oncology
Module #12 N-of-1 Trials Introduction to N-of-1 trials, including their design, conduct, and analysis, and their applications in rare diseases
Module #13 Pragmatic Clinical Trials Overview of pragmatic clinical trials, including their design, conduct, and analysis, and their applications in real-world settings
Module #14 Cluster Randomized Trials Discussion of cluster randomized trials, including their design, conduct, and analysis, and their applications in healthcare settings
Module #15 Stepped-Wedge Designs In-depth exploration of stepped-wedge designs, including their design, conduct, and analysis, and their applications in healthcare settings
Module #16 Crossover Designs Introduction to crossover designs, including their design, conduct, and analysis, and their applications in clinical trials
Module #17 Longitudinal Designs Overview of longitudinal designs, including their design, conduct, and analysis, and their applications in clinical trials
Module #18 Bayesian Methods in Clinical Trials Discussion of Bayesian methods in clinical trials, including their application in adaptive designs and decision-making
Module #19 Machine Learning in Clinical Trials Introduction to machine learning methods in clinical trials, including their application in predictive modeling and data analysis
Module #20 Digital Health Technologies in Clinical Trials Overview of digital health technologies in clinical trials, including their application in remote monitoring and data collection
Module #21 Ethical Considerations in Advanced Clinical Trial Design Discussion of ethical considerations in advanced clinical trial design, including informed consent and patient privacy
Module #22 Regulatory Considerations in Advanced Clinical Trial Design Overview of regulatory considerations in advanced clinical trial design, including FDA and EMA guidelines
Module #23 Case Studies in Advanced Clinical Trial Design Real-world examples of advanced clinical trial designs, including successes and challenges
Module #24 Future Directions in Advanced Clinical Trial Design Discussion of emerging trends and future directions in advanced clinical trial design, including artificial intelligence and precision medicine
Module #25 Course Wrap-Up & Conclusion Planning next steps in Advanced Clinical Trial Design career
