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Apprentice Mode
10 Modules / ~100 pages
Wizard Mode
~25 Modules / ~400 pages

Advanced Techniques in Bioreactor Design
( 25 Modules )

Module #1
Introduction to Bioreactor Design
Overview of bioreactor design principles, importance of advanced techniques, and course objectives
Module #2
Bioreactor Types and Classification
In-depth discussion of different bioreactor types, including stirred tank, airlift, and packed bed reactors
Module #3
Mass Transfer and Transport Phenomena
Fundamentals of mass transfer, heat transfer, and fluid dynamics in bioreactors
Module #4
Bioreactor Scale-Up and Scale-Down
Principles and challenges of scaling up and scaling down bioreactors for industrial applications
Module #5
Advanced Mixing and Aeration Techniques
Innovative mixing and aeration strategies for enhanced mass transfer, oxygenation, and mixing uniformity
Module #6
Computational Fluid Dynamics (CFD) in Bioreactor Design
Application of CFD for simulating fluid flow, heat transfer, and mass transfer in bioreactors
Module #7
Bioreactor Material Selection and Corrosion Protection
Properties and selection criteria for bioreactor materials, including stainless steel, glass, and polymers
Module #8
Sensors and Instrumentation for Bioreactor Monitoring
Overview of sensors and instrumentation for monitoring key process parameters, such as pH, temperature, and dissolved oxygen
Module #9
Advanced Process Control and Automation
Implementation of advanced control strategies, including model predictive control and artificial intelligence
Module #10
Bioreactor Sterilization and Cleaning-in-Place (CIP)
Principles and methods for bioreactor sterilization, sanitization, and cleaning-in-place
Module #11
Single-Use Bioreactors:Design and Operation
Design and operational considerations for single-use bioreactors, including bag-based and stirred tank systems
Module #12
Perfusion Bioreactors:Design and Operation
Principles and applications of perfusion bioreactors, including continuous cell culture and viral vector production
Module #13
Microbial Fermentation in Bioreactors
Microbial fermentation principles, including substrate utilization, oxygen supply, and product formation
Module #14
Mammalian Cell Culture in Bioreactors
Principles and challenges of mammalian cell culture in bioreactors, including medium design and process optimization
Module #15
Plant Cell Culture in Bioreactors
Principles and applications of plant cell culture in bioreactors, including secondary metabolite production
Module #16
Bioreactor Design for Algal Cultures
Design and operational considerations for bioreactors used in algal cultures, including photobioreactors and open ponds
Module #17
Bioreactor Integration with Downstream Processing
Interplay between bioreactor design and downstream processing, including cell harvesting, clarification, and purification
Module #18
Scalability and Cost-Effectiveness in Bioreactor Design
Economic and practical considerations for scaling up bioreactor design, including cost-benefit analysis and process intensification
Module #19
Bioreactor Design for Space and Extreme Environments
Challenges and opportunities in designing bioreactors for space exploration, extreme temperatures, and high-pressure applications
Module #20
Bioreactor Design for Personalized Medicine and Gene Therapy
Design considerations for bioreactors used in personalized medicine and gene therapy applications
Module #21
Bioreactor Design for Stem Cell Culture and Tissue Engineering
Principles and applications of bioreactor design for stem cell culture and tissue engineering
Module #22
Bioreactor Design for Environmental Applications
Design considerations for bioreactors used in environmental remediation, wastewater treatment, and bioremediation
Module #23
Bioreactor Design for Food and Feed Applications
Design principles and applications of bioreactors used in food and feed production, including protein production and fermentation
Module #24
Bioreactor Design for Biorefineries and Bioenergy
Design considerations for bioreactors used in biorefineries and bioenergy production, including biofuels and biochemicals
Module #25
Course Wrap-Up & Conclusion
Planning next steps in Advanced Techniques in Bioreactor Design career


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