Module #1 Introduction to Gene Editing Overview of gene editing, its importance, and historical context
Module #2 The Discovery of CRISPR The story behind the discovery of CRISPR-Cas9, its bacterial origins, and early research
Module #3 CRISPR Mechanism and Biology In-depth explanation of the CRISPR-Cas9 mechanism, including DNA targeting, cleavage, and repair
Module #4 Types of CRISPR Systems Overview of different CRISPR systems, including Cas9, Cas12, and Cas13, and their applications
Module #5 CRISPR Design and Targeting Principles of designing and targeting CRISPR guide RNAs, including specificity and efficiency
Module #6 CRISPR Delivery Methods Discussion of various methods for delivering CRISPR components to cells, including viral and non-viral vectors
Module #7 CRISPR Editing Techniques In-depth look at various CRISPR editing techniques, including knock-in, knock-out, and base editing
Module #8 CRISPR Safety and Off-Targeting Concerns Discussion of potential safety concerns, including off-targeting, mosaicism, and unintended consequences
Module #9 Basic Genomics and Bioinformatics for CRISPR Introduction to genomics and bioinformatics concepts necessary for CRISPR research, including genome assembly and annotation
Module #10 CRISPR Applications in Basic Research Overview of CRISPRs impact on basic research, including gene function studies and disease modeling
Module #11 CRISPR Therapeutics for Genetic Diseases Discussion of CRISPRs potential for treating genetic diseases, including sickle cell anemia and muscular dystrophy
Module #12 CRISPR and Cancer Therapy Exploration of CRISPRs potential for cancer treatment, including gene editing and gene regulation strategies
Module #13 CRISPR in Agriculture and Biotechnology Overview of CRISPRs applications in agriculture, biotechnology, and synthetic biology
Module #14 CRISPR Diagnostics and Detection Discussion of CRISPR-based diagnostic tools, including CRISPR-Cas13 and CRISPR-Cas12 systems
Module #15 Ethical and Regulatory Considerations for CRISPR Examination of ethical and regulatory challenges surrounding CRISPR, including germline editing and gene drive technologies
Module #16 CRISPR Patent Landscapes and Commercialization Overview of CRISPR patent landscapes, commercialization strategies, and intellectual property issues
Module #17 CRISPR Public Perception and Communication Discussion of strategies for communicating CRISPR research and its implications to the public and media
Module #18 CRISPR in Veterinary Medicine Exploration of CRISPRs potential applications in veterinary medicine, including animal health and welfare
Module #19 CRISPR and Synthetic Biology Discussion of CRISPRs role in synthetic biology, including genome-scale engineering and biodesign
Module #20 Advanced CRISPR Techniques In-depth look at advanced CRISPR techniques, including multiplex editing, prime editing, and CRISPR-Cas systems
Module #21 CRISPR and Microbiome Editing Overview of CRISPRs applications in microbiome editing, including phage therapy and microbiome engineering
Module #22 CRISPR and Gene Regulation Discussion of CRISPRs potential for gene regulation, including CRISPR-dCas9 systems and epigenetic modification
Module #23 CRISPR and Single-Cell Analysis Exploration of CRISPRs applications in single-cell analysis, including single-cell gene editing and transcriptomics
Module #24 CRISPR and Stem Cell Biology Overview of CRISPRs applications in stem cell biology, including gene editing in pluripotent stem cells
Module #25 CRISPR and Neurobiology Discussion of CRISPRs potential in neurobiology, including gene editing in neurons and neurological disorders
Module #26 CRISPR and Cardiovascular Disease Exploration of CRISPRs applications in cardiovascular disease, including gene editing in cardiovascular cells and tissues
Module #27 CRISPR and Immunology Overview of CRISPRs potential in immunology, including gene editing in immune cells and immunotherapy
Module #28 CRISPR and Infectious Disease Discussion of CRISPRs potential in infectious disease, including gene editing in pathogens and anti-infective therapies
Module #29 CRISPR and Personalized Medicine Exploration of CRISPRs role in personalized medicine, including precision genome editing and gene therapy
Module #30 Course Wrap-Up & Conclusion Planning next steps in CRISPR Technology and Applications career
