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WIZAPE
Apprentice Mode
10 Modules / ~100 pages
Wizard Mode
~25 Modules / ~400 pages

Genomic Data Analysis and Interpretation
( 25 Modules )

Module #1
Introduction to Genomics and Genomic Data
Overview of genomics, types of genomic data, and their applications
Module #2
Genomic Data File Formats and Quality Control
Introduction to common file formats (FASTQ, SAM, BAM, VCF) and quality control metrics (Phred scores, FASTQC)
Module #3
Genome Assembly and Annotation
Overview of genome assembly techniques (de novo, reference-based) and annotation methods (gene prediction, functional annotation)
Module #4
Introduction to Bioinformatics Tools and Pipelines
Overview of popular bioinformatics tools (BWA, SAMtools, BCftools) and pipeline management systems (Snakemake, Nextflow)
Module #5
Read Mapping and Alignment
Theory and practice of read mapping algorithms (BWA, Bowtie) and alignment formats (SAM, BAM)
Module #6
Variant Calling and Filtering
Theory and practice of variant calling algorithms (GATK, FreeBayes) and filtering strategies
Module #7
Genomic Variation and Its Consequences
Types of genomic variation (SNPs, indels, SVs), their effects on gene function, and population genetics
Module #8
Introduction to Genomic Data Visualization
Overview of genomic data visualization tools (IGV, UCSC Genome Browser, Circos) and best practices
Module #9
Genomic Data Analysis in R and Python
Introduction to R and Python libraries for genomic data analysis (e.g., GenomicRanges, PySam)
Module #10
RNA-Seq Data Analysis
Theory and practice of RNA-Seq data analysis, including quantification, differential expression, and functional enrichment
Module #11
ChIP-Seq Data Analysis
Theory and practice of ChIP-Seq data analysis, including peak calling and motif analysis
Module #12
Genomic Prediction and Machine Learning
Introduction to machine learning methods for genomic prediction (e.g., genome-wide association studies, genomic selection)
Module #13
Epigenomics and Regulatory Element Analysis
Overview of epigenetic marks, regulatory element identification, and chromatin state annotation
Module #14
Structural Variants and Copy Number Variation
Detection and interpretation of structural variants (SVs) and copy number variation (CNV)
Module #15
Cancer Genomics and Personalized Medicine
Overview of cancer genomics, somatic mutation analysis, and personalized medicine approaches
Module #16
Genomic Data Integration and Network Analysis
Methods for integrating genomic data types and network analysis techniques (e.g., co-expression networks)
Module #17
Functional Genomics and Gene Regulation
Overview of functional genomics, gene regulation, and gene expression analysis
Module #18
Genomic Data Interpretation and Clinical Reporting
Best practices for interpreting genomic data and generating clinical reports
Module #19
Genomic Data Storage and Management
Strategies for storing and managing large-scale genomic data
Module #20
Ethical and Regulatory Considerations in Genomics
Overview of ethical and regulatory issues in genomics, including informed consent and data sharing
Module #21
Case Studies in Genomic Data Analysis
Real-world examples of genomic data analysis, including disease association studies and personalized medicine applications
Module #22
Computational Tools for Genomic Data Analysis
Hands-on experience with popular computational tools for genomic data analysis (e.g., GATK, IGV, SNakemake)
Module #23
Cloud Computing and Scalable Genomic Data Analysis
Introduction to cloud computing and scalable genomic data analysis using cloud-based platforms
Module #24
Genomic Data Analysis Pipelines and Workflows
Designing and implementing genomic data analysis pipelines and workflows
Module #25
Course Wrap-Up & Conclusion
Planning next steps in Genomic Data Analysis and Interpretation career


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