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Apprentice Mode
10 Modules / ~100 pages
Wizard Mode
~25 Modules / ~400 pages

Molecular Biophysics and Structural Biology
( 25 Modules )

Module #1
Introduction to Molecular Biophysics and Structural Biology
Overview of the field, importance, and applications of molecular biophysics and structural biology
Module #2
Biophysical Techniques:An Overview
Introduction to various biophysical techniques used to study biomolecules, including spectroscopy, scattering, and microscopy
Module #3
Protein Structure and Function
Primary, secondary, tertiary, and quaternary structure of proteins, protein-ligand interactions, and enzymology
Module #4
Nucleic Acid Structure and Function
Primary, secondary, and tertiary structure of DNA and RNA, genome organization, and gene expression
Module #5
Molecular Dynamics Simulations
Introduction to molecular dynamics simulations, force fields, and applications in understanding biomolecular interactions and dynamics
Module #6
X-ray Crystallography
Principles and applications of X-ray crystallography in determining protein and nucleic acid structures
Module #7
NMR Spectroscopy
Principles and applications of NMR spectroscopy in determining protein and nucleic acid structures and dynamics
Module #8
Electron Microscopy
Principles and applications of electron microscopy in determining protein and cell structure and dynamics
Module #9
Molecular Recognition and Binding
Thermodynamics and kinetics of molecular recognition, binding affinity, and specificity
Module #10
Protein-Ligand Interactions
Types of protein-ligand interactions, binding modes, and importance in biological processes
Module #11
Membrane Biophysics
Structure, function, and dynamics of biological membranes, and membrane protein interactions
Module #12
Cellular Biophysics
Mechanical properties of cells, cellular mechanics, and cell-substrate interactions
Module #13
Biological NMR Spectroscopy
Applications of NMR spectroscopy in understanding biological processes, including protein-protein interactions and membrane protein structures
Module #14
Small-Angle X-ray Scattering (SAXS)
Principles and applications of SAXS in determining protein and nucleic acid structures and dynamics
Module #15
Cryogenic Electron Microscopy (cryo-EM)
Principles and applications of cryo-EM in determining protein and cell structure and dynamics
Module #16
Structural Bioinformatics
Computational tools and methods for analyzing and interpreting structural data, including protein structure prediction and functional annotation
Module #17
Systems Biology and Network Analysis
Methods for analyzing and modeling complex biological systems, including network analysis and systems biology approaches
Module #18
Case Studies in Biophysics and Structural Biology
In-depth analysis of selected case studies that demonstrate the power of biophysical and structural biology approaches in understanding biological processes
Module #19
Biophysics and Structural Biology in Drug Discovery
Applications of biophysical and structural biology approaches in drug discovery, including target identification, lead optimization, and structure-based design
Module #20
Computational Modeling in Biophysics and Structural Biology
Computational methods for modeling and simulating biological systems, including molecular mechanics, Monte Carlo simulations, and machine learning approaches
Module #21
Biophysical and Structural Biology Approaches to Infectious Diseases
Applications of biophysical and structural biology approaches in understanding and combating infectious diseases
Module #22
Biophysical and Structural Biology Approaches to Cancer
Applications of biophysical and structural biology approaches in understanding and combating cancer
Module #23
Biophysical and Structural Biology Approaches to Neurological Disorders
Applications of biophysical and structural biology approaches in understanding and combating neurological disorders
Module #24
Ethics and Societal Implications of Biophysics and Structural Biology
Ethical considerations and societal implications of biophysical and structural biology research, including genetic engineering and biotechnology
Module #25
Course Wrap-Up & Conclusion
Planning next steps in Molecular Biophysics and Structural Biology career


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