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Apprentice Mode
10 Modules / ~100 pages
Wizard Mode
~25 Modules / ~400 pages

Molecular Genetics and Gene Expression
( 25 Modules )

Module #1
Introduction to Molecular Genetics
Overview of molecular genetics, importance of gene expression, and course objectives
Module #2
Structure of DNA and RNA
Chemical structure, double helix model, and functions of DNA and RNA
Module #3
Replication of DNA
Mechanism of DNA replication, enzymes involved, and semi-conservative replication
Module #4
Transcription of DNA
Mechanism of transcription, RNA polymerase, and transcriptional units
Module #5
RNA Processing and Modification
Splicing, capping, and polyadenylation of RNA, and RNA editing
Module #6
Translation of RNA
Mechanism of translation, ribosomes, and protein synthesis
Module #7
Genetic Code and Mutations
The genetic code, types of mutations, and consequences of mutations
Module #8
Gene Expression Regulation
Overview of gene expression regulation, transcriptional and translational control
Module #9
Transcriptional Regulation in Prokaryotes
Lac operon, trp operon, and other examples of transcriptional regulation in prokaryotes
Module #10
Transcriptional Regulation in Eukaryotes
Enhancers, promoters, and transcription factors in eukaryotic gene regulation
Module #11
Epigenetic Regulation of Gene Expression
DNA methylation, histone modification, and chromatin remodeling
Module #12
Post-Transcriptional Regulation
RNA interference, microRNAs, and regulatory elements
Module #13
Gene Expression in Developmental Biology
Role of gene expression in developmental processes, including pattern formation and cell differentiation
Module #14
Gene Expression in Cancer
Alterations in gene expression leading to cancer, tumor suppressors, and oncogenes
Module #15
Genomics and Proteomics
High-throughput sequencing, genomics, and proteomics approaches to understanding gene expression
Module #16
Gene Regulation in Response to Environmental Stimuli
Gene expression responses to environmental stimuli, including stress and nutrient availability
Module #17
Synthetic Biology and Gene Expression
Design and construction of novel biological systems, including synthetic gene circuits
Module #18
RNA-Based Therapies
RNA interference, CRISPR-Cas9, and other RNA-based therapies for disease treatment
Module #19
Gene Therapy and Gene Editing
Principles and applications of gene therapy, including gene editing using CRISPR-Cas9
Module #20
Single-Cell Analysis and Gene Expression
Methods for analyzing gene expression at the single-cell level, including scRNA-seq
Module #21
Computational Tools for Gene Expression Analysis
Bioinformatics tools for analyzing gene expression data, including RNA-seq and microarray
Module #22
Gene Expression and Human Disease
Gene expression in the context of human disease, including genetic disorders and infectious disease
Module #23
Gene Regulation in Stem Cells
Gene expression in stem cells, including pluripotency and differentiation
Module #24
Gene Expression in Neuroscience
Gene expression in the nervous system, including neurodevelopment and neuroplasticity
Module #25
Course Wrap-Up & Conclusion
Planning next steps in Molecular Genetics and Gene Expression career


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