Molecular Mechanisms of Drug Toxicity
( 24 Modules )

Module #1
Introduction to Drug Toxicity
Overview of drug toxicity, its consequences, and importance of understanding molecular mechanisms

Module #2
Pharmacokinetics and Pharmacodynamics
Fundamentals of drug absorption, distribution, metabolism, and excretion (ADME) and its impact on toxicity

Module #3
Types of Drug Toxicity
Classification of drug toxicity:acute vs. chronic, idiosyncratic vs. dose-dependent, and reversible vs. irreversible

Module #4
Reactive Metabolites and their Role in Toxicity
Formation and consequences of reactive metabolites in drug toxicity

Module #5
Cytochrome P450 Enzymes and Drug Metabolism
Role of CYP450 enzymes in drug metabolism and toxicological consequences of CYP450-mediated reactions

Module #6
Glutathione and its Role in Detoxification
Antioxidant properties of glutathione and its involvement in drug detoxification and toxicity

Module #7
Oxidative Stress and Drug Toxicity
Mechanisms of oxidative stress and its contribution to drug-induced toxicity

Module #8
Mitochondrial Dysfunction and Drug Toxicity
Impact of mitochondrial dysfunction on drug-induced toxicity and cell death

Module #9
Apoptosis and Necrosis in Drug Toxicity
Mechanisms of apoptosis and necrosis in drug-induced toxicity and their implications

Module #10
Inflammation and Immune-Mediated Drug Toxicity
Role of inflammation and immune responses in drug-induced toxicity and hypersensitivity reactions

Module #11
Hepatotoxicity:Mechanisms and Biomarkers
Molecular mechanisms of drug-induced liver injury and biomarkers for hepatotoxicity detection

Module #12
Nephrotoxicity:Mechanisms and Biomarkers
Molecular mechanisms of drug-induced kidney injury and biomarkers for nephrotoxicity detection

Module #13
Cardiotoxicity:Mechanisms and Biomarkers
Molecular mechanisms of drug-induced cardiac injury and biomarkers for cardiotoxicity detection

Module #14
Neurotoxicity:Mechanisms and Biomarkers
Molecular mechanisms of drug-induced neurological injury and biomarkers for neurotoxicity detection

Module #15
Cancer Chemotherapy and Toxicity
Mechanisms of cancer chemotherapy-induced toxicity and strategies for mitigation

Module #16
Stem Cell Toxicity and Carcinogenicity
Mechanisms of drug-induced stem cell toxicity and carcinogenicity

Module #17
Epigenetic Modifications and Drug Toxicity
Role of epigenetic modifications in drug-induced toxicity and gene regulation

Module #18
Personalized Medicine and Pharmacogenomics
Application of pharmacogenomics in predicting drug toxicity and personalizing therapy

Module #19
In Silico Models for Drug Toxicity Prediction
Use of computational models for predicting drug toxicity and identifying potential toxic compounds

Module #20
In Vitro and In Vivo Models for Drug Toxicity Assessment
Applications and limitations of in vitro and in vivo models for drug toxicity assessment

Module #21
Biomarkers for Drug Toxicity Detection
Types and applications of biomarkers for detecting drug-induced toxicity

Module #22
Risk Assessment and Management of Drug Toxicity
Strategies for assessing and managing drug toxicity risk in patients and populations

Module #23
Regulatory Considerations for Drug Toxicity
Role of regulatory agencies in evaluating and managing drug toxicity during drug development and approval

Module #24
Course Wrap-Up & Conclusion
Planning next steps in Molecular Mechanisms of Drug Toxicity career

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Molecular Mechanisms of Drug Toxicity ( 24 Modules )

Molecular Mechanisms of Drug Toxicity
( 24 Modules )