Protein Chemistry and Function: Advanced Concepts
( 25 Modules )

Module #1
Introduction to Protein Chemistry
Overview of protein structure, function, and importance in biological systems

Module #2
Amino Acid Chemistry
Properties and classification of amino acids, including acidity, basicity, and hydrophobicity

Module #3
Protein Primary Structure
Amino acid sequence determination, Edman degradation, and Mass Spectrometry

Module #4
Protein Secondary Structure
Alpha helices, beta sheets, turns, and loops; prediction and determination methods

Module #5
Protein Tertiary Structure
Folding, domains, and motifs; X-ray crystallography and NMR spectroscopy

Module #6
Protein Quaternary Structure
Multimeric proteins, protein-ligand interactions, and oligomerization

Module #7
Protein-Ligand Interactions
Binding affinity, specificity, and kinetics; thermodynamics of binding

Module #8
Enzyme Kinetics
Michaelis-Menten kinetics, substrate inhibition, and allosteric regulation

Module #9
Protein Folding and Misfolding
Folding pathways, misfolding diseases, and protein quality control

Module #10
Protein Engineering and Design
Site-directed mutagenesis, directed evolution, and protein design algorithms

Module #11
Protein-Protein Interactions
Interactome analysis, protein-protein docking, and network biology

Module #12
Post-Translational Modifications
Phosphorylation, ubiquitination, and other PTMs; their roles in signaling and regulation

Module #13
Protein Turnover and Degradation
Proteasome-mediated degradation, autophagy, and the ubiquitin-proteasome system

Module #14
Protein Trafficking and Localization
Vesicular transport, protein targeting, and organelle biogenesis

Module #15
Protein Misfolding Diseases
Amyloidosis, neurodegenerative diseases, and cancer; therapeutic strategies

Module #16
Protein-Lipid Interactions
Lipid-protein interactions, membrane structure, and lipid rafts

Module #17
Protein-Nucleic Acid Interactions
Transcription factors, DNA-binding proteins, and chromatin remodeling

Module #18
Protein Aggregation and Amyloid Formation
Mechanisms of aggregation, amyloid fibril structure, and toxicity

Module #19
Advanced Analytical Techniques
Mass Spectrometry, NMR, and other biophysical methods for protein analysis

Module #20
Computational Tools for Protein Analysis
Homology modeling, molecular dynamics, and protein-ligand docking

Module #21
Systems Biology and Proteomics
High-throughput proteomics, protein networks, and systems biology approaches

Module #22
Synthetic Biology and Protein Design
Designing new protein functions, circuits, and pathways

Module #23
Protein-Based Therapeutics
Protein-based drugs, antibodies, and vaccines; challenges and opportunities

Module #24
Case Studies in Protein Chemistry
Real-world examples of protein chemistry and function in biological systems

Module #25
Course Wrap-Up & Conclusion
Planning next steps in Protein Chemistry and Function: Advanced Concepts career

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Protein Chemistry and Function: Advanced Concepts ( 25 Modules )

Protein Chemistry and Function: Advanced Concepts
( 25 Modules )