Protein-Protein Interactions
( 30 Modules )

Module #1
Introduction to Protein-Protein Interactions
Overview of protein-protein interactions, their importance in biological systems, and significance in biomedical research

Module #2
Types of Protein-Protein Interactions
Classification of PPIs, including obligate, non-obligate, and transient interactions

Module #3
Protein Structure and Function
Review of protein structure, function, and evolution, highlighting their impact on PPIs

Module #4
Protein-Protein Interaction Networks
Introduction to PPI networks, visualization tools, and analysis methods

Module #5
Detecting Protein-Protein Interactions
Overview of high-throughput methods for detecting PPIs, including yeast two-hybrid, co-immunoprecipitation, and mass spectrometry

Module #6
Protein-Protein Interaction Databases
Survey of popular PPI databases, including IntAct, BioGRID, and STRING

Module #7
Scoring and Predicting Protein-Protein Interactions
Introduction to scoring functions and machine learning-based methods for predicting PPIs

Module #8
Molecular Docking and Simulation
Principles of molecular docking and simulation, with applications to PPI prediction and optimization

Module #9
Protein-Protein Interaction Hotspots
Identification and characterization of hotspots, including their roles in PPI binding and regulation

Module #10
Allosteric Regulation of Protein-Protein Interactions
Mechanisms of allosteric regulation, including conformational changes and binding site cooperativity

Module #11
Post-Translational Modifications and Protein-Protein Interactions
Impact of PTMs on PPIs, including phosphorylation, ubiquitination, and acetylation

Module #12
Protein-Protein Interaction Dynamics
Experimental and computational approaches to studying PPI dynamics, including NMR, FRET, and MD simulations

Module #13
Membrane-Protein Interactions
Specialized aspects of PPIs at the membrane interface, including membrane protein structure and function

Module #14
Protein-Protein Interactions in Diseases
Roles of PPIs in disease pathology, including cancer, neurodegenerative disorders, and infectious diseases

Module #15
Targeting Protein-Protein Interactions for Therapeutics
Strategies for modulating PPIs for therapeutic benefit, including small molecules and biologics

Module #16
Computational Tools for Protein-Protein Interaction Analysis
Hands-on training with popular tools, including PyMOL, Chimera, and Cytoscape

Module #17
Case Studies in Protein-Protein Interaction Research
In-depth analysis of landmark studies and recent breakthroughs in PPI research

Module #18
Emerging Topics in Protein-Protein Interactions
Recent advances and future directions in PPI research, including single-molecule studies and artificial intelligence

Module #19
Protein-Protein Interaction Modeling and Simulation
Advanced topics in modeling and simulation of PPIs, including coarse-grained models and machine learning

Module #20
Data Integration and Visualization in Protein-Protein Interaction Analysis
Methods for integrating and visualizing large-scale PPI data, including network analysis and visualization tools

Module #21
Protein-Protein Interactions in Systems Biology
Integrating PPIs into systems-level models, including flux balance analysis and dynamic modeling

Module #22
Protein-Protein Interactions in Synthetic Biology
Designing and engineering PPIs for synthetic biological systems, including biosensors and gene circuits

Module #23
Protein-Protein Interactions in Biotechnology
Applications of PPIs in biotechnology, including biofuel production and bioremediation

Module #24
Protein-Protein Interactions in Personalized Medicine
Role of PPIs in personalized medicine, including cancer precision medicine and genetic counseling

Module #25
Protein-Protein Interaction Ethics and Policy
Ethical and policy implications of PPI research, including gene editing and biosecurity

Module #26
Computational Methods for Protein-Protein Interaction Prediction
Advanced computational methods for PPI prediction, including machine learning and deep learning

Module #27
Protein-Protein Interaction in Immunology
PPIs in the immune system, including antigen-antibody interactions and immune cell signaling

Module #28
Protein-Protein Interaction in Neurobiology
PPIs in the nervous system, including synaptic plasticity and neurological disorders

Module #29
Protein-Protein Interaction in Cancer Biology
PPIs in cancer development and progression, including tumor suppressor and oncogenic interactions

Module #30
Course Wrap-Up & Conclusion
Planning next steps in Protein-Protein Interactions career

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Protein-Protein Interactions ( 30 Modules )

Protein-Protein Interactions
( 30 Modules )