Protein Structure and Function Analysis
( 24 Modules )

Module #1
Introduction to Proteins
Overview of proteins, their importance, and significance in biological systems

Module #2
Protein Structure Introduction
Basic concepts of protein structure, primary, secondary, tertiary, and quaternary structure

Module #3
Amino Acids and Peptide Bonds
Properties of amino acids, peptide bond formation, and importance in protein structure

Module #4
Primary Structure Analysis
Methods for determining primary structure, including Edman degradation and mass spectrometry

Module #5
Secondary Structure Prediction
Methods for predicting secondary structure, including Chou-Fasman and GOR methods

Module #6
Tertiary Structure Prediction
Methods for predicting tertiary structure, including homology modeling and threading

Module #7
Quaternary Structure Analysis
Methods for analyzing quaternary structure, including X-ray crystallography and cryo-EM

Module #8
Protein Folding and Misfolding
Energy landscapes, folding pathways, and disease implications of protein misfolding

Module #9
Protein-Ligand Interactions
Methods for analyzing protein-ligand interactions, including molecular docking and dynamics

Module #10
Enzyme Structure and Function
Active site architecture, catalytic mechanisms, and enzyme regulation

Module #11
Membrane Protein Structure and Function
Unique challenges and methods for analyzing membrane protein structure and function

Module #12
Nuclear Magnetic Resonance (NMR) Spectroscopy
Principles and applications of NMR spectroscopy in protein structure determination

Module #13
X-ray Crystallography
Principles and applications of X-ray crystallography in protein structure determination

Module #14
Cryo-Electron Microscopy (Cryo-EM)
Principles and applications of cryo-EM in protein structure determination

Module #15
Bioinformatics Tools for Protein Analysis
Overview of bioinformatics tools and databases for protein analysis, including UniProt and PDB

Module #16
Sequence Alignment and Phylogenetics
Methods for sequence alignment, phylogenetic analysis, and evolutionary relationships

Module #17
Protein Function Prediction
Methods for predicting protein function, including genome context and machine learning approaches

Module #18
Protein-Protein Interactions
Methods for analyzing protein-protein interactions, including co-immunoprecipitation and protein arrays

Module #19
Structural Bioinformatics and Docking
Advanced topics in structural bioinformatics, including protein-ligand docking and molecular dynamics

Module #20
High-Throughput Screening and Fragment-Based Drug Design
Applications of protein structure and function analysis in drug discovery

Module #21
Case Studies in Protein Structure and Function
Real-world examples of protein structure and function analysis in biology and medicine

Module #22
Protein Engineering and Design
Methods for protein engineering and design, including rational design and directed evolution

Module #23
Computational Modeling of Protein Dynamics
Methods for modeling protein dynamics, including molecular dynamics and Monte Carlo simulations

Module #24
Course Wrap-Up & Conclusion
Planning next steps in Protein Structure and Function Analysis career

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Protein Structure and Function Analysis ( 24 Modules )

Protein Structure and Function Analysis
( 24 Modules )