Protein Structure and Function in Molecular Biology
( 25 Modules )

Module #1
Introduction to Proteins
Overview of proteins, their importance, and scope of the course

Module #2
Amino Acids:Building Blocks of Proteins
Properties and classification of amino acids, their role in protein structure

Module #3
Primary Structure of Proteins
Amino acid sequence, peptide bonds, and primary structure determination

Module #4
Secondary Structure of Proteins
Alpha helices, beta sheets, turns, and loops; formation and stability

Module #5
Tertiary Structure of Proteins
3D structure, folding, and interactions; globular and fibrous proteins

Module #6
Quaternary Structure of Proteins
Multimeric proteins, protein-protein interactions, and quaternary structure determination

Module #7
Protein Folding and Stability
Folding pathways, energy landscapes, and stability factors

Module #8
Protein Structural Analysis
Methods for determining protein structure, including X-ray crystallography, NMR, and EM

Module #9
Protein Function and Binding
Enzyme kinetics, substrate binding, and protein-ligand interactions

Module #10
Enzyme Mechanisms and Regulation
Enzyme catalysis, inhibition, and regulation; allosteric and cooperative effects

Module #11
Signal Transduction and Cell Signaling
Protein-mediated signaling pathways and cellular responses

Module #12
Molecular Chaperones and Protein Quality Control
Chaperone functions, protein folding, and misfolding-related diseases

Module #13
Protein-Membrane Interactions
Protein-membrane interfaces, lipid bilayers, and membrane-bound proteins

Module #14
Nuclear Magnetic Resonance (NMR) Spectroscopy
Principles and applications of NMR in protein structure determination

Module #15
X-ray Crystallography
Principles and applications of X-ray crystallography in protein structure determination

Module #16
Mass Spectrometry and Proteomics
Principles and applications of mass spectrometry in protein analysis and proteomics

Module #17
Computational Biology and Bioinformatics
Algorithms and tools for protein structure prediction, analysis, and functional annotation

Module #18
Protein Engineering and Design
Rational design, directed evolution, and computational design of proteins

Module #19
Protein-Ligand Interactions and Drug Design
Protein-ligand interactions, pharmacophore modeling, and structure-based drug design

Module #20
Protein Misfolding and Disease
Amyloidosis, prion diseases, and protein misfolding-related disorders

Module #21
Protein Trafficking and Localization
Protein targeting, translocation, and sorting; cellular trafficking pathways

Module #22
Protein Degradation and Turnover
Ubiquitin-proteasome pathway, protein degradation, and cellular recycling

Module #23
Protein-Protein Interactions and Networks
Protein interaction networks, network analysis, and systems biology

Module #24
Synthetic Biology and Protein Engineering
Design and construction of new biological pathways, circuits, and systems using protein engineering

Module #25
Course Wrap-Up & Conclusion
Planning next steps in Protein Structure and Function in Molecular Biology career

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Protein Structure and Function in Molecular Biology ( 25 Modules )

Protein Structure and Function in Molecular Biology
( 25 Modules )