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Apprentice Mode
10 Modules / ~100 pages
Wizard Mode
~25 Modules / ~400 pages

Randomized Controlled Trials
( 25 Modules )

Module #1
Introduction to Randomized Controlled Trials
Understanding the basics of RCTs, their importance in evidence-based medicine, and their application in healthcare
Module #2
History of RCTs
Exploring the evolution of RCTs, key milestones, and pioneers in the field
Module #3
RCT Design Principles
Learning about the fundamental principles of RCT design, including randomization, control groups, and blinding
Module #4
Types of RCTs
Understanding the different types of RCTs, including parallel, crossover, and cluster randomized trials
Module #5
RCT Study Phases
Exploring the various phases of an RCT, from planning to reporting
Module #6
Research Questions and Objectives
Formulating research questions, objectives, and hypotheses in RCTs
Module #7
Study Population and Sampling
Defining the study population, inclusion and exclusion criteria, and sampling methods
Module #8
Randomization Methods
Understanding different randomization methods, including simple, block, and stratified randomization
Module #9
Interventions and Control Groups
Designing and delivering interventions, and understanding control group options
Module #10
Blinding and Masking
Understanding the importance of blinding and masking in RCTs, and methods for implementation
Module #11
Outcome Measures and Endpoints
Selecting and defining outcome measures and endpoints in RCTs
Module #12
Data Management and Quality Control
Best practices for data management, quality control, and data monitoring committees
Module #13
Sample Size Calculation
Understanding sample size calculation, including formulae and software tools
Module #14
Ethical Considerations
Exploring ethical principles and guidelines in RCTs, including informed consent and risk-benefit assessment
Module #15
Regulatory Compliance
Understanding regulatory requirements, including IRB approval and FDA guidelines
Module #16
RCT Implementation and Conduct
Implementing and conducting an RCT, including site selection, staff training, and data collection
Module #17
Data Analysis and Interpretation
Analyzing and interpreting RCT data, including statistical methods and results reporting
Module #18
RCT Reporting and Publication
Writing and publishing RCT reports, including CONSORT guidelines and journal submission
Module #19
RCT Critique and Appraisal
Critiquing and appraising RCTs, including assessing quality and validity
Module #20
RCTs in Special Populations
Conducting RCTs in special populations, including pediatrics, geriatrics, and vulnerable groups
Module #21
Adaptive RCTs
Designing and conducting adaptive RCTs, including Bayesian methods and sample size re-estimation
Module #22
Pragmatic RCTs
Designing and conducting pragmatic RCTs, including real-world effectiveness and practice-based research
Module #23
RCTs in Digital Health
Conducting RCTs in digital health, including mobile health, telemedicine, and wearables
Module #24
Challenges and Limitations of RCTs
Addressing challenges and limitations of RCTs, including external validity, generalizability, and bias
Module #25
Course Wrap-Up & Conclusion
Planning next steps in Randomized Controlled Trials career


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