Toxicokinetics and Environmental Health
( 30 Modules )

Module #1
Introduction to Toxicokinetics and Environmental Health
Overview of the field, importance, and relevance to public health

Module #2
Basic Principles of Toxicology
Definitions, dose-response curves, and types of toxicity

Module #3
Pharmacokinetics and Pharmacodynamics
Absorption, distribution, metabolism, and excretion (ADME) and dose-response relationships

Module #4
Toxicokinetic Models
Compartmental models, physiologically-based pharmacokinetic (PBPK) models, and clearance

Module #5
Introduction to Environmental Health
Overview of environmental health, pollutants, and health effects

Module #6
Gastrointestinal Absorption
Mechanisms and factors influencing oral absorption

Module #7
Dermal Absorption
Mechanisms and factors influencing skin absorption

Module #8
Inhalation Toxicology
Respiratory tract absorption and deposition

Module #9
Distribution of Toxicants
Blood flow, tissue binding, and compartmental models

Module #10
Placental and Fetal Toxicology
Toxicant transfer and fetal development

Module #11
Phase I and II Metabolism
Enzymes, reactions, and pathways

Module #12
CYP450 and other Enzymes
Role in metabolism and interactions

Module #13
Renal Elimination
Glomerular filtration, tubular secretion, and reabsorption

Module #14
Hepatic Elimination
Biotransformation and biliary excretion

Module #15
Toxicant Interactions and Modulation
Enzyme induction, inhibition, and substrate competition

Module #16
Mechanisms of Toxicity
Reactive oxygen species, oxidative stress, and cellular responses

Module #17
Toxicity Testing and Biomarkers
In vitro and in vivo methods, and biomarkers of exposure and effect

Module #18
Risk Assessment and Characterization
Hazard identification, exposure assessment, and risk characterization

Module #19
Environmental Risk Assessment
Ecological risk assessment and environmental impact

Module #20
Regulatory Toxicology and Policy
Regulatory frameworks, guidelines, and policy implications

Module #21
Toxicokinetics of Nanomaterials
Unique properties and toxicity of nanomaterials

Module #22
Toxicokinetics of Emerging Contaminants
Per- and polyfluoroalkyl substances (PFAS), and other emerging contaminants

Module #23
Environmental Justice and Health Disparities
Vulnerable populations and environmental health disparities

Module #24
Toxicokinetic Modeling in Environmental Health
Applications of PBPK models in environmental health

Module #25
New Frontiers in Toxicokinetics and Environmental Health
Omics technologies, systems biology, and personalized toxicology

Module #26
Case Study:Lead Toxicity and Environmental Health
Exposure, toxicity, and health effects of lead

Module #27
Case Study:Pesticide Exposure and Human Health
Exposure, toxicity, and health effects of pesticides

Module #28
Case Study:Air Pollution and Cardiovascular Health
Exposure, toxicity, and health effects of air pollutants

Module #29
Case Study:Water Pollution and Human Health
Exposure, toxicity, and health effects of water pollutants

Module #30
Course Wrap-Up & Conclusion
Planning next steps in Toxicokinetics and Environmental Health career

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Toxicokinetics and Environmental Health ( 30 Modules )

Toxicokinetics and Environmental Health
( 30 Modules )